Betty Acquah was born in Cape Coast in the Central Region of Ghana, West Africa. She attended Wesley Girls’ High School and Holy Child School both in Cape Coast. She proceeded to the Kwame Nkrumah University of Science and Technology (KNUST), Kumasi for her B.A. (Hons) Art course where she obtained a First Class Degree. She later completed an M.F.A (Painting) Programme in the same University after a professional Art course at the Tokyo School of Art (T.S.A) in Tokyo, Japan.
She worked at the Art Gallery of the Centre for National Culture, Greater Accra Region, Accra from 1989 to 1993. She later worked at the Berj Art Gallery also in Accra from 2002 TO 2005.
Betty is a full member of Ghana Association of Visual Artists (GAVA) which is one of the agencies under the Ministry of Culture. Betty has exhibited her paintings in Ghana, Nigeria, UK, India, Germany, Spain, Japan and USA.